Antibody Response to Mannheimia Haemolytica Leukotoxin in Cattle with Respiratory Tract Disease
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منابع مشابه
Antibody Response to Mannheimia Haemolytica Leukotoxin in Cattle with Respiratory Tract Disease
In order to obtain data concerning the involvement of Mannheimia haemolytica in bovine respiratory disease (BRD) outbreaks, a serological survey was carried out on paired (acuteconvalescent) sera from 1310 beef and 810 dairy cattle collected in 262 BRD outbreaks in Italian herds during 2002-2006. No vaccination program to M. haemolytica A1 was applied in the investigated herds. For each outbrea...
متن کاملResponse of the ruminant respiratory tract to Mannheimia (Pasteurella) haemolytica.
Pneumonia is a leading cause of loss to the sheep and cattle industry throughout the world. Mannheimia (Pasteurella) haemolytica is one of the most important respiratory pathogens of domestic ruminants and causes serious outbreaks of acute pneumonia in neonatal, weaned and growing lambs, calves, and goats. M. haemolytica is also an important cause of pneumonia in adult animals. Transportation, ...
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In this study, we performed a bacteriological investigation on bovine respiratory infections. Additionally, the study evaluates the efficacy of florfenicol 30 µg produced by Rooyan Darou Company (test group) as compared to a similar drug produced by Aboraihan Company (control group). Sampling was carried out on 30 calves at two farms with 30-55% incidence rate of respiratory disorders. Nasophar...
متن کاملInflammatory cytokines enhance the interaction of Mannheimia haemolytica leukotoxin with bovine peripheral blood neutrophils in vitro.
Mannheimia (Pasteurella) haemolytica A1 produces several virulence factors that play an important role in the pathogenesis of bovine pneumonic pasteurellosis. Foremost among these is a leukotoxin (LKT) that specifically kills ruminant leukocytes. Recent evidence suggests that M. haemolytica LKT binding to bovine leukocytes is mediated by the beta(2)-integrin CD11a/CD18 (lymphocyte function-asso...
متن کاملDynamin-2-dependent targeting of mannheimia haemolytica leukotoxin to mitochondrial cyclophilin D in bovine lymphoblastoid cells.
Exotoxins which belong to the family containing the RTX toxins (repeats in toxin) contribute to a variety of important human and animal diseases. One example of such a toxin is the potent leukotoxin (LKT) produced by the bovine respiratory pathogen Mannheimia haemolytica. LKT binds to CD18, resulting in the death of bovine leukocytes. In this study, we showed that internalized LKT binds to the ...
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ژورنال
عنوان ژورنال: The Open Veterinary Science Journal
سال: 2007
ISSN: 1874-3188
DOI: 10.2174/1874318800701010007